Acetaminophen crisis bigger than opioid epidemic?

Acetaminophen, the main active ingredient in certain non-NSAID pain medications, available to adults and children without a prescription in neighborhood stores throughout the United States, is suspected by Ohio University researchers of causing its users to experience an acute psychological reaction: to lose positive empathy during the time they medicate with the drug. That would make acetaminophen the yin to MDMA’s yang.

It might also be an instigator of many social and international problems. A quarter of all US adults consume a drug containing acetaminophen every week.

In a time when scientific research is making great strides in understanding the biological origins of emotions and behavior, the emergence of strange scientific phenomena is guaranteed to offset various presumptions and the industries or governments that thrive upon them. Some call it creative destruction. Others have more derogatory names.

How the US government and the news media handles the acetaminophen revelations will reveal much about their respective priorities and whose side they’re on when it comes to drug enforcement. This should be interesting.

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22 Responses to Acetaminophen crisis bigger than opioid epidemic?

  1. primus says:

    Off Topic, sorry; what has happened to Media Awareness Program (MAP)? It appears to have stopped updating mid December last year, at least on the cannabis list.

    • DdC says:

      IDK Primus. I think MAPS was run by Richard Lake who died a while ago. DPA sponsored it and was run by Ethan Nadelmann with Soros donations. He retired and maybe there are enough drug war websites to get info? MM and CN and CC to All these.

      • DdC says:

        That should be…

        MapInc Media Awareness Project not
        MAPS Multidisciplinary Association for Psychedelic Studies

        “LSD is a psychedelic drug which occasionally causes psychotic behavior in people who have NOT taken it.”
        ― Timothy Leary

        Looks like it happens with Ganja too …

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      • allan says:

        The late Richard Lake was chief editor at MAP.

        It was not run by Ethan Nadelman. Matt Elrod and Mark Greer have always been it’s top dogs.

        MAP, it’s DrugNews archive and it’s writers’ group was a collective, almost entirely volunteer effort.

  2. NCN says:

    The proper place for acetaminophen is the garbage can. Read the label and toss in trash. Other than a small, potential placebo effect, the stuff is worthless crap.

    If it actually offered some pain relief I wouldn’t be worried about a lack of empathy. One puff of weed is a better analgesic and you don’t have to wait an hour..

    OTOH, it’s an awesome deterrent to swallowing a handful of Vicodin a few times a day. Get high on the opiate while the acetaminophen rots your liver? No thanks. It’s not a pain pill but rather a poison placed in the pathway of thrill seekers and drug abusers.

    Worthless fucking crap.

    On the social implications, I suspect the prohibitionist clan could give a shit about empathy and probably will cheer this study if it filters into their world.

  3. kaptinemo says:

    OTOH, it’s an awesome deterrent to swallowing a handful of Vicodin a few times a day. Get high on the opiate while the acetaminophen rots your liver?

    I concur; the acetaminophen mixed with pharmas serves the same purpose as methanol did during alcohol Prohibition, to deliberately poison illegal alcohol imbibers, indirectly doing what the prohibs back then wanted very much to do directly: kill those who went against their (faux) moral dictates.

    That same evil streak is in the modern-day versions of prohibs; it is a hallmark of the breed.

  4. Which drug kills more people, Tylenol or Oxycontin?
    Do other pain killers also reduce empathy? Seems like a logical extension of this study.

    • DdC says:

      Cannabis is one of the least toxic substances
      in the whole pharmacopoeia
      ~ Prof. Lester Grinspoon

      Alcohol kills more people than all other drugs combined.

      I have come to doubt whether the FDA rules should apply to cannabis. There is no question about its safety. It is one of humanity’s oldest medicines, used for thousands of years by millions of people with very little evidence of significant toxic effects. More is known about its adverse effects than about those of most prescription drugs. ~ Prof. Lester Grinspoon

      Cannabis is effective at relieving nausea and vomiting, spasticity, appetite loss, certain types of pain, and other debilitating symptoms. And it is extraordinarily safe – safer than most medicines prescribed every day. If marijuana were a new discovery rather than a well-known substance carrying cultural and political baggage, it would be hailed as a wonder drug. ~ Prof. Lester Grinspoon

      Doctors reverse recommendation on aspirin

      Cannabis is remarkably safe. Although not harmless, it is surely less toxic than most of the conventional medicines it could replace if it were legally available. Despite its use by millions of people over thousands of years, cannabis has never caused an overdose death.
      ~ Prof. Lester Grinspoon

      Drug Worriers preferred methods of treatment…

      “Marijuana never kicks down your door in the middle of the night. Marijuana never locks up sick and dying people, does not suppress medical research, does not peek in bedroom windows. Even if one takes every reefer madness allegation of the prohibitionists at face value, marijuana prohibition has done far more harm to far more people than marijuana ever could.”
      ~ William F. Buckley, Jr.

    • darkcycle says:

      Actually, oxycodone is very safe, and generally won’t cause respiratory depression unless mixed with other drugs that can cause potentiation. On it’s own, it’s very safe….like heroin. Almost all heroin overdoses are caused by drug interactions, not heroin on it’s own. Oxicodone’s therapeutic index is pretty high.

  5. No statistics I could find for oxycodone deaths that were not amalgamated with other semi synthetic opiates statistics (like fentanyl).

    450 deaths yearly from acetaminophen. 100 of then accidental.

  6. DdC says:

    We fired our bowls and the Prohibs kep a-comin’. There wasn’t nigh as many as there was a while ago. We fired once more and they begin to runnin’. On down the Mississippi to the Gulf of Mexico.

    Yeah, they ran through the briars. And they ran through the brambles. And they ran through the bushes. Where the rabbit couldn’t go. They ran so fast. That the hounds couldn’t catch ’em. On down the Mississippi to the Gulf of Mexico.

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  7. judaqartz says:

    Drugs are a harm to humanity. I hope this link can help many people.

    • NorCalNative says:

      The ones I use are medicinal and fun. Fuck off with your simple-minded bullshit. Organized religion causes way more harm to humanity.

  8. DdC says:

    Synergy is the interaction or cooperation of two or more organizations, substances, or other agents to produce a combined effect greater than the sum of their separate effects. Each human’s endocannabinoid system (ECS), requires essential supplements it can not produce itself. Same as essential vitamins and minerals or essential fatty acids Omega 3, 6 and 9. Not a drug that targets symptoms, usually by tricking the body into desired results. Profits being the motive treating over prevention or even cures. mho

    Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects

    This article is part of a themed issue on Cannabinoids in Biology and Medicine.
    To view the other articles in this issue visit

    Cannabis’s Entourage Effect:
    Why Whole Plant Medicine Matters
    Take a close look at your cannabis buds. They’re covered in a sticky dusting of crystal resin, which contains hundreds of therapeutic compounds known as cannabinoids and terpenoids. We assume you’re well acquainted with THC and CBD, but these are just two among many important players working together to produce specific effects. This interactive synergy between cannabis compounds has been coined the “entourage effect,” and once you know what this is, you’ll see why medicines containing only THC or CBD aren’t always sufficient for many medical conditions.

    CBD and THC Synergy
    CBD, abbreviated for Cannabidiol, is a natural compound found in cannabis and typically thought to be the most beneficial compound in the plant. THC, Tetrahydrocannabinol, the psychoactive compound in cannabis, is CBD’s best friend. When these two compounds are activated and ingested they synergistically complement each other and deliver exceptional medical benefits.

    The Entourage Effect:
    Synergy between cannabinoids and terpenes
    The so-called entourage effect (sometimes referred to as the ensemble effect) is a term used for the first time in a study on the interaction between various compounds present in cannabis, published in the July 1998 issue of the European Journal of Pharmacology. This text (An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity) was written by researchers and scientists including Professor Raphael Mechoulam and Shimon Ben-Shabat among others, and demonstrates the increase in activity of a given cannabinoid thanks to the presence of another compound, in this case the esters of a fatty acid. However, as research has progressed over the years, this term has been coined to refer to the interaction, or synergy between the various cannabinoids, terpenes and flavonoids present in the plant that define the effects of cannabis.

  9. Sudon't says:

    Tylenol doesn’t get you high and so, like with the antibiotics crisis, the government won’t be interested in it. The problem we have with antibiotic misuse is what the DEA ought to be kicking down doors over.

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