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March 2020
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Open Virus Thread

Hey gang, I know I haven’t been posting here (thanks so much to Servetus for keeping the site active!) Retirement is a different game, and I’ve been hard at work recovering from my shattered leg two years ago.

Some of you may have extra time during these next few weeks due to virus-related closings and self-quarantine. So what are your favorite drug-related movies and music to watch/listen to while quarantined? Let’s get some fun threads going in comments.

I’ll start off with my all-time favorite that has been a go-to for me since I was in college in the 1970s — Pink Floyd’s “Dark Side of the Moon.”

Side note: I just returned from a week in New York leading a student group, seeing Broadway plays. Unfortunately, Broadway shut down the day we were to see our last show — the first preview of “Flying Over Sunset” at Lincoln Center Theatre. It’s a musical(!) about Clare Boothe Luce, Aldous Huxley, and Carey Grant on LSD. And it has tap-dancing. The concept blows my mind and I really wish we could have seen it!

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24 comments to Open Virus Thread

  • atrocity

    I’ll start off with my all-time favorite that has been a go-to for me since I was in college in the 1970s — Pink Floyd’s “Dark Side of the Moon.”

    It’s way up on my list as well.

    I know that “quadraphonic” has become something of a punchline over the decades, but the quadraphonic version of that album takes what’s already a masterpiece to a completely new level. It’s gimmicky and stuff flies all over the room, but in that particular context the gimmickry genuinely works.

  • The only reason we have an issue is because the all seeing all knowing commander in chief, who saw it all coming, somehow forgot to get test kits for covid19 out to the public and doctors.They still are not there. Covid19 is a living testimonial to Donald Trump. So is the still existing, perpetual drug war.

    • Servetus

      Trump isn’t the problem regarding too few COVID-19 test kits. His problem derives from a common American attitude. Trump and certain other politicians don’t like no stinkin’ science, because science is hard.

      The kits employ a chemical process called PCR, the discovery of Kary Mullis who received the 1993 Nobel Prize in chemistry for his work.

      The company employing him, Cetus Corporation, made its big mistake by virtually shelving PCR while promoting its Interleukin-2 project, to the point of deliberately misrepresenting Interleukin-2’s effectiveness or test results to the FDA. Cetus got caught, and their compound was rejected. The primary problem with Cetus was the venture capitalist running it. He had little or no scientific background and therefore he couldn’t get his priorities straight on science projects—an example of the Dunning-Kruger effect. Cetus’ bankruptcy resulted in PCR being its only viable asset at liquidation, worth about $300 million in 1990s money.

      Moving forward to 1994 and the shame of the O. J. Simpson murder case, Dr Kary Mullis was scheduled to testify regarding PCR evidence found at the crime scene, but the LA prosecutors effectively barred Mullis from testifying because Kary had previously revealed he derived his inspiration for PCR after taking LSD. Therefore he was ‘controversial.’

      If a link exists between lack of preparedness for COVID-19 and the drug war, it’s that an aversion to science has been driven into the heart of American society by prohibitionists and other people or groups who represent minor factions of society, yet who wield an extraordinary influence over the individuals they exploit. It’s an old story. And it results in willful idiots like Trump or Congressman Devin Nunez second guessing science.

      • DdC

        Trump isn’t the problem regarding too few COVID-19 test kits?

        Trump never requested WHO test kits. Tried to sell his own like the vitamin scam. Fired the pandemic team. Cabinet of yesturds. Then his version didn’t work so they fell behind. Then the fox spin when Biden mentioned it as “refused” WHO. Like all spin when the washer stops we were behind in test kits and the moron keeps doubling down on bullshit spreading it to gopers everywhere. Thus is he Typhoid Mary or the Pied Piper? Seems all roads lead to Putin once again. Its the non symptom showing victims likely to spread it, therefore top priority in testing he keeps telling millions of loyal rednecks the opposite. So kids go to spring break and gopers party like its democrats attempting another coup. Pence and the Yesturds are gutless to invoke the 25th A. But Karma being what it is. United States presidential line of succession leave their biggest thorn in the drivers seat. Boss Tweet ends the same as Tweed. If he survives his own stupidity.

        • Servetus

          It’s too easy to blame Clown Trump and use him as a scapegoat to hide a messed up, neglected health system. I think there should’ve been a testing capability already built into the infrastructure long before Trump took office, emergency testing clinics ready to go in the event of an outbreak, etc., like in the Michael Crichton 1971 movie The Andromeda Strain, or treatments of transit facilities with UV radiation as part of a common sanitation ritual in airports, subways and bus terminals. Virus or PCR kits should have always been available at drugstores, like earthquake kits at hardware stores. It might have even stopped some regular flu epidemics.

          Of course Trump was going to fumble the ball on a response to the outbreak. That’s why the medical system should’ve been made Trump-proof before a viral disaster like Trump stepped into the Oval Office. One mere clown should never have the exclusive authority to defund and close down a pandemic response team or office already in place. The same with climate remediation or the Paris Accord.

          Nor should one person be allowed to alter, cut back, or block the renewal of existing nuclear treaties that will result in a proliferation of nuclear weapons—something Trump is expected to do if re-elected and once the treaties are due for signing. To idiot-proof the country long ago in anticipation of someone like Trump assuming office would have meant recognizing the source of Trump’s ascension to power.

          Trump’s base elected Trump along with his trumpery because they always vote their particular religion. Anti-intellectual, anti-science, anti-environment, while casting themselves as ‘pro-life,’ everything else is secondary to their glorious apocalyptic finale, including public health, as if they were some suicide cult. That’s why I choose to think the base voting for Trump are responsible for the spread of COVID-19 and that they still pose an existential threat to themselves and others even with the virus gone. They’ll elect Trump again, if they live long enough.

          If that’s not bad enough, Noam Chomsky anticipates that a Trump re-election would mean no effort will be made by the US to throttle the contagious growth of fascism throughout the world:

          https://truthout.org/articles/we-cant-let-covid-19-drive-us-into-authoritarianism/

  • Servetus

    No word yet whether cannabis combats COVID-19. I’ve always had fewer colds when consuming cannabis, so to be on the safe side I’m continuing my usual consumption and staying home.

    Here are some useful tips brought to you by science, not politicians, on the latest COVID-19 survival data re surfaces and aerosols. COVID-19 is now officially designated 2 (SARS-CoV-2):

    The virus that causes COVID-19 remains for several hours to days on surfaces and in aerosols, a new study published in the New England Journal of Medicine found.

    The study suggests that people may acquire the coronavirus through the air and after touching contaminated objects. Scientists discovered the virus is detectable for up to three hours in aerosols, up to four hours on copper, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel. […]

    AAAS Public Release: Study reveals how long COVID-19 remains infectious on cardboard, metal and plastic

    • DdC

      Hope everyone’s getting by okay.

      Haven’t had a cold since 69. No ABs or Big Pharma in my medicine chest. Kept a Cerebral Palsy client off of ABs 10 years with a shot of food grade Hemp seed Oil. My guess is the HO as fuel burns 125 calories quicker than digesting a steak and not as much wasted on digestion. Microbes can’t build up a colony large enough to overload into an UTI in his case. It will lower a temp a few 10ths. CBD and Ganja for Ibuprofen side effect rash and swelling.

      That’s not treating viral infections. Except side effects of it. Without an ECS infrastructure and still S#1, not taught to many future doctors, won’t be easy. Then with permission forced to use Mississippi Schwag.

      So observing it 50 years it seems CBs feed the ECS that puts things back to their original DNA at the cellular level. On a daily consistent diet, not treating symptoms as big Pharma does. The “high” may be residual, more than the ECS can take in? In that case it should be able to deal with a virus or the damage. If the ECS deals with foreign toxins removed from the blood into the lymph system to the bladder, causing edema. If the ECS can id and remove the virus or starve it. ??? Good thing about Ganja and Hemp over ABs is they don’t just nuke them all.

      I’ve wondered about cardboard packages. Hard surfaces for days. CDC is silent, but recommended not to pass joints or share bongs. Guess I’ll have to dust off the old shotgun for company.

      I’m social distancing. Trump thinks that’s a good idea, says this will never be a socialist country! Then licks KFC off his fingers.

      Got masks?

      Study on Antibacterial Mechanism of Hemp Fiber

      10 Benefits of Hemp Seed Oil for Great Health
      Anti-inflammation
      Enhanced immune function

      HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD

      HEMP SEED OILS
      AND THE FLOW OF LIFE FORCE

      Unique cannabis properties can help provide relief from SYMPTOMS of flu and other viruses

      Newsom of California
      Orders Californians to Stay at Home

      After uproar within cannabis industry, dispensaries deemed essential services

  • Son of Sam Walton

    My job won’t allow me to be quarantined, since I’m deemed essential. (Thank You, Covid-19 for making me feel special). But if I was quarantined: the movie, Dazed and Confused, Half Baked, Friday, The Doors (and the band). Music: the Dead, and anything 90’s gangster-rap and European Black Metal. Books: Ivo Andric’s ‘The Bridge on the Drina’ about the famous bridge that that kept the Ottomans and Austrians keep control of the whole of the Bosnian region, essential for the ebb and flow of the Archdukes’s assassination . . . with all the people impaled by the Ottoman’s and morbid bridge construction rituals, it isn’t a sleepy read.

    And I too believe in the viral fighting powers of Cannabis. So I bought a higher in CBD strain with a magnificent terp profile since flavors in foods tend to indicate specific minerals and vitamins that we as humans might be needing or craving.

  • Servetus

    Michael Crichton’s 1971 flick, ‘Dealing: Or the Berkeley-to-Boston Forty-Brick Lost-Bag Blues’, is good for a nostalgia trip down marijuana lane.

  • NCN

    Two cannabis cultivation movies, Homegrown (98) and Savages (2012).

    The Wire, The Sopranos, Breaking Bad, and Son’s of Anarchy are binge worthy.

    Getting really tired of this distancing shit. Socialism distancing is why our Wealth Care system is so systemically effed in the first place.

    From my cynical-ass perch, this virus is almost worth it just to see the Republican cult attempts at actual governance. Our for-profit Wealth Care system is pathologically bipartisan.

    A nation that allows itself to be health care victims probably deserves what comes our way.

  • Servetus

    CBD fights resistant bacteria and reduces the amount of antibiotics needed in a treatment, from the University of Southern Denmark:

    24-Mar-2020—Since the discovery of penicillin in 1928 by Sir Alexander Fleming, antibiotics have saved millions of lives from fatal infections world-wide. However, with time bacteria have developed mechanisms to escape the effects of antibiotics – they have become resistant.

    With fewer antibiotics available to treat resistant bacterial infections, the possibility of entering a pre-antibiotic era is looming ahead.

    Alternative strategies are being explored and helper compounds are attracting attention. Helper compounds are non-antibiotic compounds with the capability of enhancing the efficacy of antibiotics.

    How to boost antibiotics

    One such helper compound has been suspected to be cannabidiol (CBD); a cannabinoid from the cannabis plant. Now a research team from University of Southern Denmark, has published a scientific study proving the effect of CBD. […]

    When we combined CBD and antibiotics, we saw a more powerful effect than when treating with antibiotics alone. So, in order to kill a certain number of bacteria, we needed less antibiotics…According to the researchers, the combination of CBD and antibiotics may be a novel treatment of infections with antibiotic resistant bacteria.

    How do the bacteria die?

    Three things happened with the Staphylococcus aureus bacteria, when the researchers treated them with the combination in their study:

    The bacteria could no longer divide normally.

    The expression of certain key genes (cell division and autolysis genes) in the bacteria was lowered.

    The bacterial membrane became unstable.

    AAAS Public Release: New study: Cannabis helps fight resistant bacteria

  • DdC

    ☛ New Jersey Gov. Phil Murphy (D) exempted medical cannabis dispensaries from a stay-at-home order issued amid the coronavirus outbreak.
    twitter.com/DdC

    ☛ Ohio Gov. Mike DeWine’s (R) stay-at-home order exempts medical cannabis businesses from a shutdown during the coronavirus crisis.

    ☛ Colorado Gov. Jared Polis (D) issued an executive order allowing marijuana businesses to do curbside pickup and letting doctors issue medical cannabis recommendations via telemedicine during the coronavirus pandemic.

    ☛ Nevada Gov. Steve Sisolak (D) ordered that all marijuana sales be made via deliveries during the coronavirus outbreak.

    ☛ California regulators deemed cannabis retails outlets to be essential businesses that can stay open amid the coronavirus pandemic.

    ☛ Pennsylvania regulators are allowing patients to have medical cannabis brought to their cars outside of dispensaries and are letting caregivers make deliveries to an unlimited number of patients amid the coronavirus pandemic.

    ☛ New Mexico regulators said that medical cannabis businesses are essential and can stay open during the coronavirus outbreak. They also allowed curbside pickup and delivery services, extended expiring patient and caregiver cards for 90 days and temporarily suspended background checks for new employees.

    ☛ Oregon regulators approved rules to allow curbside delivery of marijuana at licensed retail locations and to increase medical cannabis sales limits.

    ☛ The Drug Enforcement Administration issued a statement on its move to allow doctors to issue prescriptions for controlled substances to patients whom they have not examined in-person during the coronavirus outbreak.

    ☛ Illinois Gov. J.B. Pritzker’s (D) coronavirus stay-at-home order declares marijuana dispensaries and cultivation facilities to be essential businesses.

  • DdC

    ☛ 3D Printing Hemp Homes
    https://t.co/wY6tU771Ow?amp=1
    ☛ Hemp House Pulls CO2 From Air
    https://t.co/sLH1fSCrki?amp=1
    ☛ Battery ecp
    https://t.co/rnBq0P0evk?amp=1
    ☛ Car
    https://t.co/LlKKOhFJYE?amp=1

    Five major cannabinoids, or consituents of cannabis, “showed potent activity against a variety of [MRSA].

    ☛ Cannabinoids May Fight Antibiotic-Resistant MRSA
    https://t.co/eAO8FS6gXz?amp=1

    Antibiotic potential of cannabis:
    CBG compound resistant to MRSA

    The cannabinoid CBG prevented the ability of MRSA bacteria to form biofilms, which are communities of microorganisms that attach to each other and to surfaces; and it destroyed pre-formed biofilms and cells resistant to antibiotics. CBG achieved this by targeting the cell membrane of the bacteria.
    Feb 27, 2020

  • Servetus

    New molecular probes for opioid receptors:

    25-MAR-2020 — [Opioid] painkillers have excellent efficacy, but also severe side effects. On the one hand, there is the danger of dependency, on the other hand, patients may become tolerant – i.e. the effectiveness of the drugs decreases with repeated use. This means that the dose must be increased over time to achieve the same effect…Decker now presents new findings in this field in the journal “Angewandte Chemie” …

    The receptors form short-lived pairs …”It is still unclear whether the analgesic effect of opioids is mediated by individual receptors or whether it is necessary for the receptors to aggregate into pairs or larger molecular complexes,” said Decker. Evidence has already been found for all these possibilities.

    “We found that most opioid receptors exist as individual entities in the cell membrane. However, a small proportion forms pairs of two. Although the lifespan of these pairs is short, they might contribute to the function of this important family of receptors.” […]

    Due to the importance of these new findings, “Angewandte Chemie” has classified the publication of the JMU researchers as “highly important”. It is freely available on the Web. In addition, the work was selected for one of the journal covers.

    University of Würzburg: https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/new-molecular-probes-for-opioid-receptors/

  • DonDig

    .
    .
    There had been a playbook for pandemic response here, and they talk about it in this Politico article. I didn’t read the whole thing but it seems to have been at least somewhat ignored.

    https://www.politico.com/news/2020/03/25/trump-coronavirus-national-security-council-149285

  • Servetus

    Prosocial behavior in opioid addicted animals is restored using chemogenetic activation:

    A new study in animals suggests that the social and interpersonal problems associated with opioid addiction might be reversible.

    Researchers in the Arizona State University Department of Psychology previously used an animal model of opioid addiction and empathy to show that animals stopped prosocial behaviors – helping another animal – when heroin was available. The same research group has now shown that activating the anterior insula restored prosocial behaviors in opioid-addicted animals. The study will be published in Social Neuroscience and is now available online.

    “As a master’s student, I led support groups for opioid addicts, and the biggest problems people wanted help dealing with were social. Our finding in an animal model of opioid addiction that chemogenetic activation of the anterior insula restores prosocial behavior suggests a glimmer of hope that some of the social behavioral deficits in opioid addiction are not permanent,” said Seven Tomek, who just defended her doctoral dissertation at ASU. Tomek is first author on the paper and received training in substance abuse treatment while earning her master’s in clinical psychology from the University of North Carolina, Wilmington. […]

    “We designed our animal study based on work in people showing that damage in the anterior insula area – from a stroke for example – was correlated with easily quitting cigarette smoking,” Tomek said. “This brain area is also important for motivation and emotions in people.”

    AAAS Public Release: Anterior insula activation restores prosocial behavior in animal model of opioid addiction

    Original Publication: https://www.tandfonline.com/doi/abs/10.1080/17470919.2020.1746394?journalCode=psns20

  • Tony Aroma

    One of the most underrated stoner movies IMO is Smiley Face (2007). Is it the Up In Smoke of the new millennium? I don’t know, that’s a rhetorical question.

  • I’ve been using marijuana medically for a long time, to reduce pain. But I haven’t seen any movies about it or listened to songs. I’ll take a note, make sure I see your references. Did you know the difference between medicinal and recreational weeds? I was recently interested in that question. In this article, https://dr-weedy.com/what-is-the-difference-between-medical-and-recreational-weed/, I found all the answers I was looking for. The information is useful, I suggest.

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